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	Comments on: X203 &#124; Living longer by blocking interleukin-11	</title>
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	<link>https://increaselifespan.net/2024/07/27/x203-longevity-interleukin-11/</link>
	<description>Science based supplements for health and increase lifespan</description>
	<lastBuildDate>Wed, 21 Aug 2024 08:42:44 +0000</lastBuildDate>
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		<title>
		By: increaselifespan		</title>
		<link>https://increaselifespan.net/2024/07/27/x203-longevity-interleukin-11/#comment-4907</link>

		<dc:creator><![CDATA[increaselifespan]]></dc:creator>
		<pubDate>Wed, 21 Aug 2024 08:42:44 +0000</pubDate>
		<guid isPermaLink="false">https://increaselifespan.net/?p=567#comment-4907</guid>

					<description><![CDATA[In reply to &lt;a href=&quot;https://increaselifespan.net/2024/07/27/x203-longevity-interleukin-11/#comment-4905&quot;&gt;Mikael - Italy&lt;/a&gt;.

in the mean time, rapamycin, targeted supplementation, sleep and sports works excellent!]]></description>
			<content:encoded><![CDATA[<p>In reply to <a href="https://increaselifespan.net/2024/07/27/x203-longevity-interleukin-11/#comment-4905">Mikael &#8211; Italy</a>.</p>
<p>in the mean time, rapamycin, targeted supplementation, sleep and sports works excellent!</p>
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		<title>
		By: increaselifespan		</title>
		<link>https://increaselifespan.net/2024/07/27/x203-longevity-interleukin-11/#comment-4906</link>

		<dc:creator><![CDATA[increaselifespan]]></dc:creator>
		<pubDate>Wed, 21 Aug 2024 08:39:34 +0000</pubDate>
		<guid isPermaLink="false">https://increaselifespan.net/?p=567#comment-4906</guid>

					<description><![CDATA[In reply to &lt;a href=&quot;https://increaselifespan.net/2024/07/27/x203-longevity-interleukin-11/#comment-4905&quot;&gt;Mikael - Italy&lt;/a&gt;.

X203 is still in the early stages of clinical development, and it may take several years before it becomes available to the public. The first clinical trials, which started in 2023, are focused on assessing the safety, tolerability, and pharmacokinetics of the IL-11 inhibitor in healthy volunteers 
https://www.boehringer-ingelheim.com/us/boehringer-ingelheim-begins-clinical-development-first-class-treatment-fibrotic-diseases 

Assuming the trials go well, it could progress through Phase 2 and Phase 3 trials, which typically take several more years. If successful, X203 might be available for specific medical conditions related to fibrosis in the late 2020s or early 2030s. Its use for life extension purposes would likely require additional research and regulatory approval beyond that timeframe  https://english.elpais.com/science-tech/2024-07-17/a-simple-monthly-injection-allows-mice-to-live-25-longer-and-free-from-diseases.html

Probably Chinese labs will have it within 2 to 5 years and will offer it as a research chemical in the EU and USA, but this is just a guess.]]></description>
			<content:encoded><![CDATA[<p>In reply to <a href="https://increaselifespan.net/2024/07/27/x203-longevity-interleukin-11/#comment-4905">Mikael &#8211; Italy</a>.</p>
<p>X203 is still in the early stages of clinical development, and it may take several years before it becomes available to the public. The first clinical trials, which started in 2023, are focused on assessing the safety, tolerability, and pharmacokinetics of the IL-11 inhibitor in healthy volunteers<br />
<a href="https://www.boehringer-ingelheim.com/us/boehringer-ingelheim-begins-clinical-development-first-class-treatment-fibrotic-diseases" rel="nofollow ugc">https://www.boehringer-ingelheim.com/us/boehringer-ingelheim-begins-clinical-development-first-class-treatment-fibrotic-diseases</a> </p>
<p>Assuming the trials go well, it could progress through Phase 2 and Phase 3 trials, which typically take several more years. If successful, X203 might be available for specific medical conditions related to fibrosis in the late 2020s or early 2030s. Its use for life extension purposes would likely require additional research and regulatory approval beyond that timeframe  <a href="https://english.elpais.com/science-tech/2024-07-17/a-simple-monthly-injection-allows-mice-to-live-25-longer-and-free-from-diseases.html" rel="nofollow ugc">https://english.elpais.com/science-tech/2024-07-17/a-simple-monthly-injection-allows-mice-to-live-25-longer-and-free-from-diseases.html</a></p>
<p>Probably Chinese labs will have it within 2 to 5 years and will offer it as a research chemical in the EU and USA, but this is just a guess.</p>
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		<title>
		By: Mikael - Italy		</title>
		<link>https://increaselifespan.net/2024/07/27/x203-longevity-interleukin-11/#comment-4905</link>

		<dc:creator><![CDATA[Mikael - Italy]]></dc:creator>
		<pubDate>Wed, 21 Aug 2024 08:08:44 +0000</pubDate>
		<guid isPermaLink="false">https://increaselifespan.net/?p=567#comment-4905</guid>

					<description><![CDATA[I need this medicine to become young...lololo !!!

when will it come to market..or will the pharmaceutical mafia buy the invetor ???

sick people, heart disease and cancer makes billions. healthy people makes no no money to big Mafia pharma.]]></description>
			<content:encoded><![CDATA[<p>I need this medicine to become young&#8230;lololo !!!</p>
<p>when will it come to market..or will the pharmaceutical mafia buy the invetor ???</p>
<p>sick people, heart disease and cancer makes billions. healthy people makes no no money to big Mafia pharma.</p>
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